Round 1 vs GWS:
St Kilda will open its season against the Giants at Etihad Stadium in the early timeslot on a Sunday afternoon. The Saints have never lost to GWS, and won a hard-fought battle against them at the same venue in round two last year.

Round 2 vs Gold Coast:
Sam Fisher’s 200th game.*

Round 3 vs Collingwood:
St Kilda’s solitary Friday night outing for 2015 will be at the MCG against the Magpies.

Broadcast live on Channel Seven, this will be a chance for the club to demonstrate its progression on the big stage in front of a packed house. A key player in this advancement has been Jack Newnes, and he is due to play his 50th game in round three.

Round 4 vs Carlton:
The Saints third trip to Wellington promises to be a special affair in 2015. On the 100th anniversary of the Gallipoli landings, St Kilda will take on Carlton at Westpac Stadium in one of five Anzac Day fixtures. The match will be held at 1.10pm New Zealand time and broadcast into Melbourne at 11.10am.

Round 10 vs Hawthorn:
St Kilda faces a huge test at Etihad Stadium in round 10, taking on reigning premiers Hawthorn for the Blue Ribbon Cup.

Following the 2014 thrashing at the hands of the Hawks, this shapes as another critical test to determine just how far the Saints have progressed in 12 months. Assuming he plays the first nine games of the year, Jack Steven will play 100th AFL match in round 10.

Round 13 vs Western Bulldogs:
Sean Dempster’s 150th game for St Kilda.*

Round 18 vs Port Adelaide:
Leigh Montagna’s 250th AFL game.*

Round 19 vs Fremantle:
Nick Riewoldt’s 300th AFL match.*

Round 20 vs North Melbourne:
For the second year in a row, St Kilda’s loyal Tasmanian contingent of supporters will have the chance to see their team play live at Blundstone Arena. The game is one of two traditional 2.10pm matches in 2015.

*Assuming they don't miss a game to this point.