Callum Wilkie will lead St Kilda on the biggest day of its 150-year calendar, taking the reins as captain for this weekend's milestone match at the MCG.

The vice-captain assumes the mantle after scans yesterday afternoon confirmed a broken collarbone for skipper Jack Steele - sustained during Saturday's 51-point win over the Western Bulldogs - which will rule him out of action for at least the next month.

It won't be the first time Wilkie has shouldered the responsibility as leader, having taken up the role last season for one match against Brisbane, again due to Steele being sidelined following shoulder surgery.

After serving in the club's leadership group for the past two seasons, the runner-up at last year's Trevor Barker Award was elevated to the role of vice-captain last month.

"It's obviously a huge honour," Wilkie said at this morning's media opportunity at the MCG alongside CEO Simon Lethlean, Essendon's Jye Caldwell, Melbourne City's Mathew Leckie and Grand Prix Division Manager of Motorsport, David Corrigan.

"Firstly to Steeley and his character to play on after breaking his collarbone, I'm super proud to be behind him and have him as captain. He leads from the front and his pain tolerance to be able to get back on the field and give himself to the team is nothing short of remarkable.

"I don't know if I could have done that, but he does it year on year whenever he gets injured. He's incredible. It shows to our young players that you've got to fight right up to the end. We were up by 30, 40 points and he came back on and gave it everything.

"He said after the game it wasn't feeling too bad and then he showed me the next game and it was shattered.

Round 3 at the 'G will celebrate 150 years of the red, white and black, with the club's pre-game ceremony to incorporate several past greats who have been irreplaceable in seeing the club through to its major milestone.

St Kilda will pay further respect to its on-field legends earlier in the evening when it inducts its latest group of player's into the club's Hall of Fame, as well as salute the 1966 Premiership team as part of the prestigious function.

The current-day Saints will commemorate the club's most sacred day by wearing its 150th Year Heritage Guernsey, mirroring the look of the Grand Final side with the reintroduction of a collar, black cuffs and enlarged and embroidered Crest.

"It's going to be special," Wilkie said. 

"There have been some amazing players to have played for the club. It was only last week where we were walking around the locker room with a few of the boys looking at some of the names on the wall a little bit in awe at who's been there before us.

"We've got some greats who have now joined as assistant coaches and everyone respects them so much and what they've done for the game in Robert Harvey, Lenny Hayes and Brendon Goddard.

"Everyone always taps into their knowledge and their passion for the club, and it's probably what you've seen out (there) in the first couple of games.

"They've taught us what it means to wear a St Kilda jumper and us a group are going to be proud to wear it this weekend.

"Hopefully we can put in a good performance for the fans."