There were positives aplenty to come from St Kilda's 14.8 (92) to 11.8 (74) win against Essendon at the MCG on Saturday night, but unfortunately there were also more injury concerns for the already hard-hit Saints.

Jimmy Webster has a facial injury after a head clash late in the game while Mason Wood finished the match on the bench nursing a sore shoulder.

Already boasting the league's longest injury list, including captain Jack Steele and star full forward Max King, Ross Lyon has had to dig deep into the club's playing stocks and has so far been rewarded as his side sits undefeated after three rounds.

"My understanding is it (Webster's injury) is a cheekbone under a little bit of pressure," Lyon said after the win.

"And Mason Wood's a bit of a shoulder, but we'll assess it in the cold light of day.

"I think Jimmy's definitely out, but Mason Wood we'll assess tomorrow."

To lose Wood could be particularly costly for the Saints as he has been in career-best form to start the season.

The former Kangaroo is averaging just under 24 disposals a game, up on his previous best season last year where he managed just over 16 touches each outing.

Mason Wood competes in the air as St Kilda initiates on its first-quarter blitz. Photo: AFL Photos.

"His first three games have been outstanding to be honest," Lyon said. "And again he stood up in the last quarter.

"Everyone's got their own story, haven't they? He'd been on an AFL list, been injured a lot, so he's put in a lot of time on his body and his preparation and he's grabbed his second opportunity.

"A lot of people do that. You look back and you think 'what did I leave on the table at the other place?'

"Footy mortality sharpens you up pretty quick."